The study aims to investigate how a specific drug called Gefitinib affects the sensitivity of human lung adenocarcinoma tumors (a type of non-small cell lung cancer) grown in nude mice (immunocompromised mice without functioning immune systems, commonly used as models for studying human diseases) when exposed to radiation.

The study design involved four groups:

1. Control group: This group received no treatment and served as a baseline.

2. Irradiation alone group: These mice only received radiation therapy but not any other treatments.

3. Gefitinib alone group: In this group, the mice were given daily doses of gefitinib by gavage (through the stomach) without receiving radiation therapy.

4. Radiation combined with gefitinib group: This was the experimental arm where both radiation and gefitinib were used together.

The study evaluated several outcomes:

1. Percentage of tumor growth inhibition

2. Growth delay time (the difference in time it took for tumors to double their size between treated and control groups)

3. Regrowth delay time (the additional time taken after treatment cessation before the tumor resumed its original rate of growth)

To summarize, this study was designed to explore whether combining gefitinib with radiation therapy could effectively reduce or even completely stop the growth of human lung adenocarcinoma tumors that had been transplanted into nude mice.

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